Association of early interleukin-6 level with injury severity and mortality in trauma patients: Systematic review and meta-analysis

Table 2 Interleukin-6 values of survivors and non-survivors, mean ± SD

Ref.	Survivors		Non-survivors		Significant difference	Time of IL-6 measure
	No. patients	IL-6 (pg/mL)	No. patients	IL-6 (pg/mL)
Akkose et al[14], 2007	14	0.15 ± 0.05	6	0.18 ± 0.08	> 0.05	On arrival
Stensballe et al[20], 20091	236	28 ± 5	29	200 ± 65	< 0.05	On arrival
						12 hours
Taniguchi et al[19], 20161	201	60 ± 10	7	420 ± 165	< 0.05	On arrival
Yagmur et al[17], 2005	21	86 ± 77	17	146 ± 134	0.05	On arrival
Bogner et al[15], 2009	47	NR	11	NR	< 0.05	On arrival, 6 hours
Ebrahimpour et al[13], 2018	136	251.27 ± 33.07	25	250.24 ± 21.96	> 0.05	24 hours
	136	223.53 ± 25.33	25	276.84 ± 12.51	< 0.05	48 hours
Gupta et al[9], 20151	77	70 ± 82	37	346 ± 445	< 0.05	On arrival
	77	96 ± 75	26	653 ± 576	< 0.05	72 hours

¹Approximated values from the figure.

NR: Not reported; IL: Interleukin.