Impact of magnesium on the clearance of lactate in critically sick patients with sepsis: Randomized clinical trial

Table 3 Comparison of various outcomes, mean ± SD/median (range)

Parameter	Group M (n = 69)	Group P (n = 69)	Mean difference (95%CI)	P value
Time to lactate clearance (hours)	5.73 ± 2.19	8.54 ± 2.72	-2.81 (-3.65 to -1.99)	0.0011
Lactate clearance (%)
Day 1	18.88 ± 1.80	12.61 ± 1.94	6.26 (5.63-6.89)	0.0011
Day 2	30.02 ± 4.30	23.34 ± 4.76	6.68 (5.15-8.20)	0.0011
Day 3	50.74 ± 6.06	37.94 ± 4.53	12.80 (11.00-14.60)	0.0011
Vasopressor dose (mcg/kg/minute)
Day 1	0.6 (0.1-1.2)	0.7 (0.3-0.9)		0.0742
Day 2	1.2 (0.6-1.6)	1.5 (1.2-1.7)		0.0222
Day 3	1.5 (0.9-2.3)	1.9 (1.5-2.3)		0.0332
Duration of ICU stay (days)	8 (3-15)	12 (5-19)		0.0012
Duration of hospital stay (days)	12 (4-24)	16 (9-25)		0.0012
28-day mortality; n (%)	15 (21.73)	24 (34.78)		0.123

¹Independent sample t-test.

²Mann-Whitney U test.

³χ² test.

M: Magnesium group; P: Placebo group; CI: Confidence interval; ICU: Intensive care unit.