Impact of magnesium on the clearance of lactate in critically sick patients with sepsis: Randomized clinical trial

Table 2 Comparison of clinical and laboratory parameters, n (%)/median (range)

Parameter	Group M (n = 69)	Group P (n = 69)	P value
Serum lactate at diagnosis (mmol/L)	2.78 (2.11-6.35)	2.67 (2.11-7.71)	0.9881
APACHE-II score at ICU admission	19.00 (5 -32)	20.00 (10-32)	0.1921
SOFA score
Day 1	6.00 (2-13)	6.00 (2-13)	0.2651
Day 2	6.00 (2-13)	6.00 (2-13)	0.1361
Day 3	7.00 (2-13)	6.00 (2-12)	0.1311
Serum bilirubin (mg/dL)
Day 1	0.5 (0.3-4.7)	0.5 (0.2-4.7)
Day 2	0.5 (0.2-3.8)	0.5 (0.2-3.8)	0.6381
Day 3	0.5 (0.3-4.7)	0.5 (0.2-4.7)	0.8491
Serum creatinine (mg/dL)
Day 1	0.80 (0.3-1.2)	0.72 (0.3-1.2)	0.5701
Day 2	0.7 (0.4-1.0)	0.7 (0.4-1.0)	0.6841
Day 3	0.8 (0.4-1.2)	0.7 (0.3-1.1)	0.2371
Urine output (mL/day)
Day 1	1430 (820-1980)	1430 (800-2000)	0.3791
Day 2	1350 (820-2000)	1450 (800-1990)	0.0901
Day 3	1430 (930-2000)	1350 (800-1980)	0.8811
Ventilator requirement
Day 1	34 (49.28)	34 (49.28)	1.0002
Day 2	38 (55.07)	42 (60.87)	0.4902
Day 3	30 (43.48)	36 (52.17)	0.3072

¹Mann-Whitney U test.

²χ² test.

M: Magnesium group; P: Placebo group; APACHE: Acute Physiology and Chronic Health Evaluation; ICU: Intensive care unit; SOFA: Sequential Organ Failure Assessment.