Sex differences in serious outcomes among critically ill adults following endotracheal intubation

Table 3 Univariate and multivariate logistic regression analysis for predicting serious outcomes among males following endotracheal intubation

Parameters	Univariate		Multivariate-initial level		Multivariate-final level
	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
Age ≥ 45 years	2.06 (1.46-2.92)	< 0.001	1.82 (1.14-2.91)	0.012	1.8 (1.15-2.8)	0.009
Shift duty (morning-evening)	1.68 (1.2-2.36)	0.003	1.49 (0.97-2.29)	0.071	1.52 (1.12-2.33)	0.048
Altered mental status	1.07 (0.75-1.52)	0.704
Coma (GCS ≤ 6)	1.26 (0.57-2.81)	0.569
Fever	2.06 (1.29-3.29)	0.003	1.21 (0.68-2.18)	0.515
Drowsiness (< 15)	2.78 (1.86-4.18)	< 0.001	1.74 (1.03-2.94)	0.037	1.72 (1.05-2.81)	0.03
Shortness of breath	1.55 (1.1-2.18)	0.013	1.07 (0.64-1.77)	0.801
Seizures	0.46 (0.25-0.85)	0.014	0.97 (0.43-2.18)	0.941
Vomiting/blood/fluid	1.7 (1.03-2.8)	0.037	1.06 (0.55-2.03)	0.865	1.65 (1.07-2.56)	0.024
Hypoxia	4.35 (2.42-7.81)	< 0.001	3.78 (1.88-7.6)	< 0.001	3.96 (1.97-7.92)	< 0.001
Metabolic acidosis	2.19 (1.24-3.88)	0.007	1.48 (0.74-2.95)	0.268
Anticipated decline	1.97 (1.16-3.37)	0.013	2.09 (1.07-4.08)	0.031	2.05 (1.05-3.99)	0.034
Respiratory distress	1.51 (1.05-2.16)	0.025	1.29 (0.8-2.09)	0.294
Polytrauma	0.7 (0.28-1.73)	0.433
Isolated trauma	0.57 (0.26-1.25)	0.162
Gunshot	0.45 (0.13-1.57)	0.210
Shock index ≥ 0.9	3.18 (2.37-4.27)	< 0.001	2.81 (1.72-4.58)	< 0.001	2.81 (1.74-4.55)	< 0.001
pH group ≤ 7.3	1.92 (1.47-2.509)	< 0.001	2.52 (1.62-3.9)	< 0.001	2.55 (1.65-3.93)	< 0.001

OR: Odds ratio; CI: Confidence interval; GCS: Glasgow Coma Scale.