Predicting acute kidney injury in septic shock patients using inflammatory indices in the intensive care unit

Figure 10  Diagnostic performance across probability thresholds threshold-dependent performance metrics for the multilayer perceptron model. At a 0.3 threshold, the model achieved high sensitivity (99.9%) but low specificity (0.2). Increasing the threshold to 0.5 balanced sensitivity (77%) and specificity (45%), while a 0.7 threshold improved specificity (82%) at the expense of sensitivity (40%). The optimal threshold (0.5) yielded the best overall accuracy (68%), representing the preferred trade-off for clinical application.