Predicting acute kidney injury in septic shock patients using inflammatory indices in the intensive care unit

Table 3 Multivariate logistic regression with forward selection of risk factors associated with acute kidney injury

		β	SE	P value	Odds ratio	95%CI for EXP(β)
						Lower	Upper
Model 1	SOFA score	0.04	0.01	0.005	1.04	1.01	1.06
	Blood urea nitrogen	0.01	0.003	< 0.001	1.01	1.00	1.01
	Serum creatinine	1.24	0.07	< 0.001	3.46	3.00	4.00
	Neutrophils	0.001	0.0001	< 0.001	1.00	1.00	1.00
	Monocytes	0.001	0.001	0.09	1.00	1.00	1.00
	Potassium	-0.164	0.05	0.001	0.85	0.76	0.94
	Total bilirubin	-0.05	0.016	0.002	0.95	0.92	0.98
	ACEi	0.44	0.15	0.003	1.56	1.16	2.08
	Vasopressors	0.16	0.01	0.09	1.17	0.98	1.41
Model 2	Caucasian	-0.075	0.027	0.005	0.93	0.88	0.98
	Malignancy	-0.41	0.12	< 0.001	0.66	0.52	0.83
	Immunosuppression	-0.26	0.12	0.034	0.76	0.60	0.98
	CKD	1.23	0.10	< 0.001	3.40	2.82	4.19
	Vasopressors	0.44	0.06	< 0.001	1.55	1.39	1.73
	Diabetes	0.55	0.20	0.006	1.74	1.17	2.58
	ACEi	0.45	0.10	< 0.001	1.58	1.29	1.93
	A2RB	0.51	0.18	0.005	1.68	1.16	2.41
	Factor 1 (inflammatory/hematologic)	0.10	0.03	< 0.001	1.10	1.04	1.17
	Factor 2 (metabolic/renal/inflammatory)	0.26	0.03	< 0.001	1.30	1.23	1.39
Model 3	Caucasian	0.37	0.10	< 0.001	1.44	1.19	1.74
	Malignancy	-0.39	0.12	0.001	0.68	0.54	0.85
	Immunosuppression	-0.27	0.13	0.034	0.77	0.60	0.98
	CKD	1.19	0.10	< 0.001	3.29	2.70	4.01
	Vasopressors	0.30	0.07	< 0.001	1.35	1.19	1.54
	Diabetes	0.56	0.20	0.006	1.75	1.18	2.59
	ACEi	0.47	0.10	< 0.001	1.60	1.30	1.96
	A2RB	0.52	0.19	0.005	1.69	1.17	2.43
	Factor 1 (Inflammatory/hematologic)	0.12	0.03	< 0.001	1.13	1.06	1.20
	Factor 2 (metabolic/renal/inflammatory)	0.24	0.03	< 0.001	1.27	1.19	1.34
	SOFA score	0.04	0.01	< 0.001	1.04	1.01	1.05

ACEi: Angiotensin converting enzyme inhibitor; A2RB: Angiotensin 2 receptor antagonist; CKD: Chronic kidney disease; SOFA: Sequential Organ Failure Assessment.