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Retrospective Cohort Study
©Author(s) (or their employer(s)) 2026.
World J Crit Care Med. Mar 9, 2026; 15(1): 114318
Published online Mar 9, 2026. doi: 10.5492/wjccm.v15.i1.114318
Table 2 Baseline demographic and Clinical characteristics of intensive care unit patients with septic shock, n (%)

Without AKI
With AKI
P value
OR
95%CI for OR
Male gender2523 (49.4)3428 (52.3)0.0021.1241.0451.210
Ethnicity
African American436 (8.5)762 (11.6)< 0.001
Asian96 (1.9)123 (1.9)
Caucasian3989 (78.1)4891 (74.6)
Hispanic259 (5.1)376 (5.7)
Native American33 (0.6)32 (0.5)
Other294 (5.8)368 (5.6)
Hypertension473 (9.8)619 (9.4)0.7301.0220.9021.159
Diabetes88 (1.7)203 (3.1)< 0.0011.8241.4162.349
Chronic obstructive pulmonary disease512 (10)586 (8.9)0.0480.8820.7780.999
Hyperlipidemia94 (1.8)193 (2.9)< 0.0011.6191.2622.077
Cerebrovascular disease84 (1.6)135 (2.1)0.1011.2580.9561.656
Malignancy342 (6.7)304 (4.6)< 0.0010.6780.5780.795
Chronic kidney disease259 (5.1)1154 (17.6)< 0.0014.0023.4794.605
Cardiomyopathy10 (0.2)19 (0.3)0.3111.4830.6893.191
Heart failure460 (9.0)679 (10.4)0.0141.1681.0311.323
Immunosuppression315(6)271(4)0.00010.650.550.77
Cirrhosis128 (2.6)144 (2.2)0.2450.8670.6811.103
Corticosteroids656 (12.8)729 (11.1)0.0040.8500.7590.951
Ventilation2155 (42.2)2997 (45.7)< 0.0011.1551.0731.244
Diuretics712 (13.9)1185 (18.1)< 0.0011.3631.2321.508
Angiotensin converting enzyme inhibitor345 (6.8)602 (9.2)< 0.0011.3971.2171.603
Angiotensin 2 receptor antagonist119 (2.3)199 (3.0)0.0201.3131.0431.653
Vasopressors1576 (30.9)2975 (45.4)< 0.0011.8641.7262.013


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