©Author(s) (or their employer(s)) 2026.
World J Crit Care Med. Mar 9, 2026; 15(1): 113235
Published online Mar 9, 2026. doi: 10.5492/wjccm.v15.i1.113235
Published online Mar 9, 2026. doi: 10.5492/wjccm.v15.i1.113235
Table 1 Epidemiology and outcomes of intensive care unit admission following hematopoietic stem cell transplantation
| Parameter | Autologous HSCT | Allogeneic HSCT | Overall |
| ICU admission rate | 3.3%-8% | 16%-30% | 8.8%-23% |
| Timing of ICU admission | |||
| Early (Days 0-30) | Conditioning toxicity, engraftment syndrome | Conditioning toxicity, SOS, early infections | 25%-40% of admissions |
| Intermediate (Days 31-100) | Infections | Acute GVHD, infections, TA-TMA | 30%-45% of admissions |
| Late (> 100 days) | Late effects | Chronic GVHD, opportunistic infections, BOS | 20%-35% of admissions |
| Primary indications | |||
| Respiratory failure | 30%-50% | 50%-70% | 40%-70% |
| Sepsis/septic shock | 25%-40% | 35%-50% | 30%-50% |
| Neurological complications | 5%-10% | 10%-20% | 8%-15% |
| Organ support requirements | |||
| Mechanical ventilation | 25%-35% | 35%-55% | 38% |
| Vasopressor support | 20%-30% | 30%-50% | 25%-45% |
| Renal replacement therapy | 5%-10% | 15%-25% | 10%-20% |
| Survival outcomes | |||
| ICU survival (30-day) | 70%-85% | 55%-70% | 57.7% |
| Hospital survival | 65%-80% | 45%-65% | > 60% |
| 1-year survival | 55%-70% | 30%-50% | 35%-55% |
- Citation: Gupta N, Maurya P, Maurya P, Gupta A. Critical care in hematopoietic stem cell transplantation: Common complications and management. World J Crit Care Med 2026; 15(1): 113235
- URL: https://www.wjgnet.com/2220-3141/full/v15/i1/113235.htm
- DOI: https://dx.doi.org/10.5492/wjccm.v15.i1.113235