Death in patients with immune-mediated inflammatory diseases in the intensive care unit: First week data

Table 5 Predictors of lethal outcome (data on the seventh day of staying in the intensive care unit), median (interquartile range)

Predictor	Se	Sp	OR (95%CI)	RR (95%CI)	Р value
Maximum HR > 115 per minute	70.0	91.7	25.7 (2.2-298.5)	4.1 (1.5-11.5)	0.003
CRP > 19.1 mg/L	100.0	92.3	-	-	0.00003
Albumin ≤ 35 g/L	88.9	61.5	12.8 (1.2-135.6)	5.5 (0.8-36.9)	0.018
Total protein ≤ 55 g/L	88.9	84.6	44.0 (3.4-573.4)	9.6 (1.4-64.3)	0.0007
Glasgow Coma Scale score ≤ 12 points	70.0	92.3	28.0 (2.4-323.7)	4.4 (1.5-12.5)	0.002
SOFA > 3 points	100.0	83.3	-	-	0.00009
Need in MV	70.0	91.7	25.7 (2.2-298.5)	4.1 (1.5-11.5)	0.003
Meeting the EULAR/ACR/PRINTO 2016 criteria	44.4	84.6	4.4 (0.6-32.5)	2.1 (0.9-5.4)	0.015
Treatment with bDMARD	30.0	100.0	-	-	0.034
Anticoagulant therapy	30.0	15.4	0.08 (0.01-0.59)	0.28 (0.1-0.8)	0.008

Se: Sensitivity; Sp: Specificity; CI: Confidence interval; OR: Odds ratio; RR: Respiratory rate; HR: Heart rate; CRP: C-reactive protein; SOFA: Sequential Organ Failure Assessment; MV: Mechanical ventilation; EULAR: European League Against Rheumatism; ACR: American College of Rheumatology; PRINTO: Paediatric Rheumatology International Trials Organisation; bDMARD: Biological disease-modifying antirheumatic drugs.