Death in patients with immune-mediated inflammatory diseases in the intensive care unit: First week data

Table 3 Predictors of lethal outcome (data on the third day of staying in the intensive care unit), median (interquartile range)

Predictor	Se	Sp	OR (95%CI)	RR (95%CI)	Р value
Leukocytes ≤ 4.0 × 109/L	60.0	97.1	46.5 (4.4-492.1)	7.9 (3.0-21.0)	0.00001
Platelets ≤ 63 × 109/L	70.0	88.2	17.5 (3.2-96.6)	7.0 (2.2-22.5)	0.0002
Hemoglobin ≤ 87 g/L	80.0	82.4	18.7 (3.1-111.0)	8.6 (2.1-35.2)	0.0002
CRP > 129 mg/L	66.7	78.8	8.0 (1.6-40.2)	4.5 (1.3-15.1)	0.009
Triglycerides > 2.45 mmol/L	75.0	81.8	13.5 (0.9-207.6)	3.0 (0.8-44.0)	0.039
Albumin ≤ 28 g/L	77.8	86.2	21.9 (3.3-145.2)	8.6 (2.1-35.1)	0.0002
Creatinine > 83.5 μmol/L	66.7	83.5	11.6 (2.2-62.2)	5.1 (1.5-16.9)	0.002
pH ≤ 7.38	55.6	89.7	12.1 (2.1-71.1)	4.7 (1.6-13.5)	0.004
Glasgow Coma Scale score ≤ 10 points	70.0	91.2	24.1 (4.0-145.6)	7.9 (2.5-25.2)	0.00005
SOFA > 2 points	100.0	71.0	-	-	0.00009
Mechanical ventilation	70.0	93.1	31.5 (4.4-226.5)	7.8 (2.5-24.1)	0.00004
No IVIG treatment	96.9	27.3	11.6 (1.1-127.3)	3.2 (0.6-17.5)	0.018
Blood transfusion	27.3	21.9	0.11 (0.02-0.5)	0.2 (1.1-3.3)	0.003

Se: Sensitivity; Sp: Specificity; CI: Confidence interval; OR: Odds ratio; RR: Respiratory rate; CRP: С-reactive protein; SOFA: Sequential Organ Failure Assessment; IVIG: Intravenous immunoglobulin.