Death in patients with immune-mediated inflammatory diseases in the intensive care unit: First week data

Table 1 General characteristics of patients hospitalized in the intensive care unit and their main outcomes, n (%)/median (interquartile range)

General characteristics of patients	n = 51
Patients’ demography
Gender, male	23 (45.1)
Age, months	121 (60, 182)
Disease groups
MIS-C	18 (35.3)
Systemic rheumatic diseases	24 (47.1)
Infections	9 (17.6)
Preceding immunosuppression	18 (35.3)
Assessment of MAS
Hscore, points	97 (72, 140)
Correspondence to criteria
HLH 2004	4/48 (8.3)
MAS 2005	35/48 (72.9)
EULAR/ACR/PRINTO	19/48 (39.6)
ICU admission and outcomes
Time to ICU admission from the onset of disease, days	10.0 (6.0, 30.0)
Duration of stay in ICU, days	6.0 (4.0, 15.0)
Lethal outcome	13 (25.5)
Days before deaths	39 (17, 62)

MIS-C: Multisystem inflammatory syndrome associated with coronavirus disease 2019 in children; MAS: Macrophage activation syndrome; HLH: Hemophagocytic lymphohistiocytosis; EULAR: European League Against Rheumatism; ACR: American College of Rheumatology; PRINTO: Paediatric Rheumatology International Trials Organisation; ICU: Intensive care unit.