Optic nerve sheath diameter trajectories and mortality in children with clinically relevant elevated intracranial pressure

Table 3 Linear mixed effects model for dynamic changes in optic nerve sheath diameter within 48 hours of pediatric intensive care unit admission in association with the survival outcome at discharge (n = 69)

Random effect analysis1	Variance	SD
Intercept	0.084	0.289
Residual	0.047	0.217
Fixed effect analysis	Estimate	SE	95%CI	P value
Baseline ONSD levels	0.837	0.032	0.774-0.899	< 0.001
GCS at admission	-0.047	0.015	-0.076 to -0.018	< 0.01
Death (yes)	0.125	0.058	0.011-0.238	0.03

¹Random effect accounted for 23% from linear mixed effects model.

GCS: Glasgow Coma Scale; ONSD: Optic nerve sheath diameter.