Acute kidney injury in critically ill patients with traumatic brain injury: A single-center retrospective cohort study

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Crit Care Med. Dec 9, 2025; 14(4): 110079
Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.110079

Table 4 Outcome

Variable	Non-AKI group (n = 295)	AKI group (n = 36)	P value
LOS in hospital (day)	22 (12-58)	18 (7-41)	0.05²
LOS in ICU (day)	8 (5-17)	18 (7-24.5)	0.008²
Mechanical ventilation			0.017¹
Yes	228 (77.29)	34 (94.44)
No	67 (22.71)	2 (5.56)
Ventilator day	5 (1-12)	17.5 (7-24.5)	< 0.001²
Glasgow coma scale at discharge or death from ICU	14 (11-15)	3 (3-3)	< 0.001²
Tracheostomy			0.794¹
Yes	68 (23.05)	9 (25)
No	227 (76.95)	27 (75)
Brain death			< 0.001¹
Yes	18 (6.1)	20 (55.56)
No	277 (93.9)	16 (44.44)
28-day mortality			< 0.001¹
Yes	22 (7.46)	22 (61.11)
No	273 (92.54)	14 (38.89)
More than 28-day mortality	Non-AKI group (n = 273)	AKI group (n = 14)	< 0.001¹
Yes	3 (1.1)	7 (50)
No	270 (98.9)	7 (50)

¹Pearson χ² test.

²Mann-Whitney test.

Values are presented as n (%), median (interquartile range). AKI: Acute kidney injury; ICU: Intensive care unit; LOS: Length of stay.

Citation: Wankhade BS, El Kholi MHIA, Alrais ZF, Elkhouly AES, Naidu GAK, Patel AA, Sameer M, Abbas MS, Elbasier NNF, El Hadi AF. Acute kidney injury in critically ill patients with traumatic brain injury: A single-center retrospective cohort study. World J Crit Care Med 2025; 14(4): 110079
URL: https://www.wjgnet.com/2220-3141/full/v14/i4/110079.htm
DOI: https://dx.doi.org/10.5492/wjccm.v14.i4.110079

Wankhade BS, El Kholi MHIA, Alrais ZF, Elkhouly AES, Naidu GAK, Patel AA, Sameer M, Abbas MS, Elbasier NNF, El Hadi AF. Acute kidney injury in critically ill patients with traumatic brain injury: A single-center retrospective cohort study. World J Crit Care Med 2025; 14(4): 110079 [PMID: 41377544 DOI: 10.5492/wjccm.v14.i4.110079]

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