Haemostasis and beyond: The expanding role of desmopressin in intensive care

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Crit Care Med. Dec 9, 2025; 14(4): 108370
Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.108370

Table 5 Key effects of desmopressin on sodium

Effect	How it happens	Clinical impact
Lowers sodium levels (hyponatremia risk)	Retains water, diluting sodium	Risk of dilutional hyponatremia if fluid intake is not controlled
Stabilizes sodium correction in SIADH	Slows rapid sodium rise by promoting water retention	Prevents osmotic demyelination syndrome
Does not directly alter sodium excretion	Primarily affects water balance, not sodium transport	Sodium levels change due to dilution effects

Citation: Vinjamuri S, Tiwari E, Kataria S, Juneja D. Haemostasis and beyond: The expanding role of desmopressin in intensive care. World J Crit Care Med 2025; 14(4): 108370
URL: https://www.wjgnet.com/2220-3141/full/v14/i4/108370.htm
DOI: https://dx.doi.org/10.5492/wjccm.v14.i4.108370

Vinjamuri S, Tiwari E, Kataria S, Juneja D. Haemostasis and beyond: The expanding role of desmopressin in intensive care. World J Crit Care Med 2025; 14(4): 108370 [PMID: 41377554 DOI: 10.5492/wjccm.v14.i4.108370]

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