Stroke metrics, safety, and outcomes of telemedicine-administered thrombolytics for acute ischemic stroke: A meta-analysis

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

World J Crit Care Med. Dec 9, 2025; 14(4): 107570
Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.107570

Table 1 Prespecified eligibility criteria

Participants	Interventions	Comparison	Outcomes	Study types
Age > 18 years; acute stroke patients receiving intravenous thrombolytics	Intervention group: Telemedicine (audio and video) evaluation by neurology specialist	Control group: In-person evaluation by neurology specialist	Primary outcome: Door-to-needle time. Secondary outcomes: sICH; mortality; mRS ≤ 2; only studies evaluating one or more of these outcomes	RCT; observational cohort study

sICH: Symptomatic intracranial hemorrhage; RCT: Randomized controlled trial.

Citation: Loggini A, Schwertman A, Hornik J, Dallow K, Hornik A. Stroke metrics, safety, and outcomes of telemedicine-administered thrombolytics for acute ischemic stroke: A meta-analysis. World J Crit Care Med 2025; 14(4): 107570
URL: https://www.wjgnet.com/2220-3141/full/v14/i4/107570.htm
DOI: https://dx.doi.org/10.5492/wjccm.v14.i4.107570

Loggini A, Schwertman A, Hornik J, Dallow K, Hornik A. Stroke metrics, safety, and outcomes of telemedicine-administered thrombolytics for acute ischemic stroke: A meta-analysis. World J Crit Care Med 2025; 14(4): 107570 [PMID: 41377547 DOI: 10.5492/wjccm.v14.i4.107570]

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