Length of stay, duration of mechanical ventilation, mortality, and acute kidney injury in acute respiratory failure requiring endotracheal intubation

Table 5 Correlation of epidemiological and respiratory/arterial blood gases data with occurrence of acute kidney injury, n (%)

Characteristic	No AKI, n = 60	AKI, n = 71	P value
Age, years	65.4 ± 2	69 ± 1.5	0.18
Sex
Female	14 (35.9)	25 (64.1)	0.14
Male	46 (50)	46 (50)
Comorbidities
No	10 (62.5)	6 (37.5)	0.15
Yes	50 (43.6)	65 (56.5)
APACHE score	19.5 ± 1	23 ± 1	0.007
CVC days	14.7 ±1.9	19.8 ± 2.3	0.03
Medical admission
No	19 (63.3)	12 (36.7)	0.04
Yes	41 (41.4)	59 (58.6)
COVID-19
No	40 (61.5)	25 (38.5)	< 0.001
Yes	20 (30.3)	46 (69.7)
PaO2/FiO2	150.5 ± 8.6	138.1 ± 5.8	0.4
PaO2, mmHg	88.8 ± 3.6	93.7 ± 3	0.3
PaCO2, mmHg	42.7 ± 1.5	43.4 ± 1.5	0.8
pH	7.33 ± 0.01	7.31 ± 0.01	0.2
Lactate, mmol/L	3.3 ± 0.4	3.2 ± 0.4	0.5
Ppeak, cmH2O	34 ± 1.5	38.4 ± 1	< 0.001
PEEP, cmH2O	10.7 ± 0.5	12.7 ± 0.4	0.001
RR, breaths/minute	24.6 ± 0.8	26.6 ± 0.7	0.02
MV, L	10.4 ± 0.3	11 ± 0.3	0.2

AKI: Acute kidney injury; APACHE: Acute physiology and chronic health evaluation; CVC: Central venous catheter; COVID-19: Coronavirus disease 2019; PaO₂: Arterial oxygen partial pressure; FiO₂: Fraction of inspired oxygen; PaCO₂: Arterial carbon dioxide partial pressure; Ppeak: Peak airway pressure; PEEP: Positive end-expiratory pressure; RR: Respiratory rate; MV: Minute ventilation.