Length of stay, duration of mechanical ventilation, mortality, and acute kidney injury in acute respiratory failure requiring endotracheal intubation

Table 2 Comparison of epidemiological and respiratory/arterial blood gases data amongst survivors, n = 41, and non-survivors, n = 90, n (%)

Characteristic	Survivors	Non-survivors	P value
Age, years	61.8 ± 2.7	70 ± 1.2	0.009
Sex
Female	11 (28.2)	28 (71.8)	0.619
Male	30 (32.6)	62 (67.4)
Comorbidities
No	10 (62.5)	6 (37.5)	0.004
Yes	31 (27)	84 (73)
APACHE score	18 ± 1.1	23 ± 0.9	0.001
CVC days	20.3 ± 4.1	16.1 ± 1.3	0.563
Medical admission
No	16 (53.3)	15 (46.7)	0.004
Yes	25 (25.3)	75 (74.7)
COVID-19
No	32 (49.2)	33 (50.8)	< 0.001
Yes	9 (13.6)	57 (86.4)
PaO2/FiO2	177.5 ± 10	128.4 ± 5.2	< 0.001
PaO2, mmHg	99.5 ± 5.2	87.8 ± 2.3	0.001
PaCO2, mmHg	38.4 ± 1.6	45.1 ± 1.2	0.05
pH	7.36 ± 0.01	7.3 ± 0.01	0.002
Lactate, mmol/L	3 ± 0.4	3.4 ± 0.4	0.413
Ppeak, cmH2O	31.4 ± 1.2	38.7 ± 1.1	< 0.001
PEEP, cmH2O	10 ± 0.5	12.6 ± 0.4	< 0.001
RR, breaths/minute	23.7 ± 0.7	26.5 ± 0.7	0.001
MV, L	10.3 ± 0.3	11 ± 0.3	0.05

APACHE: Acute physiology and chronic health evaluation; CVC: Central venous catheter; COVID-19: Coronavirus disease 2019; PaO₂: Arterial oxygen partial pressure; FiO₂: Fraction of inspired oxygen; PaCO₂: Arterial carbon dioxide partial pressure; Ppeak: Peak airway pressure; PEEP: Positive end-expiratory pressure; RR: Respiratory rate; MV: Minute ventilation.