Retrospective Cohort Study
Copyright ©The Author(s) 2025.
World J Crit Care Med. Sep 9, 2025; 14(3): 106387
Published online Sep 9, 2025. doi: 10.5492/wjccm.v14.i3.106387
Table 1 Baseline characteristics of septic shock hospitalization, stratified by race/ethnicity, n (%)
Variables
NHW (n = 2391504)
NHB (n = 524535)
Hispanics (n = 405145)
Others (n = 260320)
P value
Age67.69 ± 14.7563.38 ± 15.3962.58 ± 16.7465.64 ± 16.37< 0.001
Female1130920 (47.3)256595 (48.9)182825 (45.1)118395 (45.5)
Hospital bed size0.0035
Small450774 (18.8)93780 (17.9)71750 (17.7)45055 (17.3)
Medium689954 (28.9)151535 (28.9)124735 (30.8)75240 (28.9)
Large1250775 (52.3)279220 (53.2)208660 (51.5)140025 (53.8)
Hospital teaching status< 0.001
Rural197030 (8.2)22795 (4.3)6850 (1.7)8350 (3.2)
Urban non-teaching506685 (21.2)77955 (14.9)89720 (22.1)51625 (19.8)
Urban teaching1687789 (70.6)423785 (80.8)308575 (76.2)200345 (77.0)
Admission< 0.001
Elective102625 (4.3)16710 (3.2)14610 (3.6)9960 (3.8)
Missing3385 (0.1)765 (0.1)460 (0.1)330 (0.1)
Primary payment coverage< 0.001
Medicare1609239 (67.3)317860 (60.6)206445 (51.0)144475 (55.5)
Medicaid252545 (10.6)100525 (19.2)97345 (24.0)51335 (19.7)
Private insurance403975 (16.9)76220 (14.5)65855 (16.3)47415 (18.2)
Self-pay55375 (2.3)14470 (2.8)23785 (5.9)9115 (3.5)
No charge4000 (0.2)1100 (0.2)1590 (0.4)550 (0.2)
Other63630 (2.7)13530 (2.6)9660 (2.4)7080 (2.7)
Missing2740 (0.1)830 (0.2)465 (0.1)350 (0.1)
Median household income, $< 0.001
1-28999647215 (27.1)266905 (50.9)158690 (39.2)63695 (24.5)
29000-35999651700 (27.3)110845 (21.1)100835 (24.9)53255 (20.5)
36000-46999575325 (24.1)82855 (15.8)86380 (21.3)61235 (23.5)
47000+475645 (19.9)54170 (10.3)50045 (12.4)74660 (28.7)
Missing41620 (1.7)9760 (1.9)9195 (2.3)7475 (2.9)
Hospital region< 0.001
Northeast431420 (18.0)82520 (15.7)51890 (12.8)51375 (19.7)
Midwest551250 (23.1)100175 (19.1)24830 (6.1)25200 (9.7)
South958410 (40.1)288280 (55.0)158370 (39.1)66325 (25.5)
West450424 (18.8)53560 (10.2)170055 (42.0)117420 (45.1)
Comorbidities
Congestive heart failure879550 (36.8)205260 (39.1)120295 (29.7)84100 (32.3)< 0.001
Cardiac arrhythmias1036490 (43.3)193560 (36.9)133205 (32.9)96575 (37.1)< 0.001
Valvular heart diseases225415 (9.4)37995 (7.2)25705 (6.3)19340 (7.4)< 0.001
Pulmonary circulatory disorders233610 (9.8)62480 (11.9)33895 (8.4)23065 (8.9)< 0.001
Peripheral vascular disease264480 (11.1)54685 (10.4)33775 (8.3)23630 (9.1)< 0.001
Hypertension1497265 (62.6)365370 (69.7)247160 (61.0)159030 (61.1)< 0.001
Chronic lung disease732830 (30.6)124415 (23.7)73185 (18.1)53225 (20.4)< 0.001
Diabetes804655 (33.6)221880 (42.3)190655 (47.1)109730 (42.2)< 0.001
Chronic kidney disease683580 (28.6)215725 (41.1)128585 (31.7)81530 (31.3)< 0.001
Liver disease442915 (18.5)97530 (18.6)94405 (23.3)56030 (21.5)< 0.001
Anemia170080 (7.1)45145 (8.6)30785 (7.6)19385 (7.4)< 0.001
AIDS8715 (0.4)14495 (2.8)4640 (1.1)1970 (0.8)< 0.001
Cancer333525 (13.9)73540 (14.0)49790 (12.3)39595 (15.2)< 0.001
Rheumatologic disorders95845 (4.0)20310 (3.9)15035 (3.7)8565 (3.3)< 0.001
Coagulopathy615690 (25.7)151545 (28.9)126840 (31.3)81305 (31.2)< 0.001
Obesity410760 (17.2)89985 (17.2)76005 (18.8)31645 (12.2)< 0.001
Fluid and electrolyte disorders1865804 (78.0)424535 (80.9)322810 (79.7)207375 (79.7)< 0.001
Alcohol abuse184730 (7.7)33290 (6.3)33860 (8.4)18570 (7.1)< 0.001
Drug abuse138285 (5.8)27410 (5.2)21515 (5.3)10910 (4.2)< 0.001
Depression326810 (13.7)42430 (8.1)36215 (8.9)19590 (7.5)< 0.001
Smoking328675 (13.7)59840 (11.4)30585 (7.5)20615 (7.9)< 0.001
Elixhauser comorbidity score5.51 ± 2.205.82 ± 2.225.31 ± 2.215.33 ± 2.18< 0.001