Management of intracranial hypertension with and without invasive intracranial pressure monitoring

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Sep 9, 2025 (publication date) through Jul 18, 2025

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Crit Care Med. Sep 9, 2025; 14(3): 105645
Published online Sep 9, 2025. doi: 10.5492/wjccm.v14.i3.105645

Table 5 Treatments that are not recommended for patients with severe traumatic brain injury

Mannitol by non-bolus continuous intravenous infusion
Scheduled infusion of hyperosmolar therapy
Lumbar cerebrospinal fluid drainage
Furosemide
Routine use of steroids
Routine use of therapeutic hypothermia to temperatures below 35 ℃
High-dose propofol to achieve burst suppression
Routinely decreasing PaCO₂ below 30 mmHg
Routinely raising cerebral perfusion pressure above 90 mmHg

Citation: Bianchini L, Matos PMPG, Roepke RML, Besen BAMP. Management of intracranial hypertension with and without invasive intracranial pressure monitoring. World J Crit Care Med 2025; 14(3): 105645
URL: https://www.wjgnet.com/2220-3141/full/v14/i3/105645.htm
DOI: https://dx.doi.org/10.5492/wjccm.v14.i3.105645