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©The Author(s) 2025.
World J Crit Care Med. Sep 9, 2025; 14(3): 102834
Published online Sep 9, 2025. doi: 10.5492/wjccm.v14.i3.102834
Published online Sep 9, 2025. doi: 10.5492/wjccm.v14.i3.102834
Table 2 Summary of studies on the effects of early enteral nutrition in patients with cardiothoracic disorders including those in the intensive care unit
Ref. | Type of study | Study population | Outcomes |
Zheng et al[44], 2025 | Retrospective cohort study | 1846 patients with cardiogenic shock | EEN was associated with improved survival outcomes and decreased length of hospitalization |
Shen et al[45], 2024 | Retrospective RCT | 720 patients with 4 days or greater CTICU stay | EEN was associated with shorter length of hospital and ICU stay and reduced incidence of respiratory and blood infections |
Better glycemic control and reduced insulin needs | |||
No significant difference found in long-term survival | |||
Efremov et al[46], 2017 | Prospective RCT | 40 mechanically ventilated, post-cardiac surgery patients who received either standard isocaloric EEN or calorie-dense, protein-rich EEN | EEN led to reduced requirements for parenteral nutrition |
Lu et al[47], 2023 | Retrospective review | 65 patients, 42 of which received VV-ECMO and 23 whom received VA-ECMO | EEN safe and well-tolerated by patient’s receiving ECMO for more than 24 hours |
EEN associated with higher success rates of weaning off ECMO and reduced mortality | |||
Delayed EN group to had significantly higher feeding intolerance as compared with the EEN group |
- Citation: Yanamaladoddi V, D’Cunha H, Charley E, Kumar V, Sohal A, Youssef W. Early enteral nutrition in critically-ill patients. World J Crit Care Med 2025; 14(3): 102834
- URL: https://www.wjgnet.com/2220-3141/full/v14/i3/102834.htm
- DOI: https://dx.doi.org/10.5492/wjccm.v14.i3.102834