Early enteral nutrition in critically-ill patients

Table 1 A summary of studies exploring the effect of early enteral nutrition in burns patients on a variety of outcomes including intensive care unit length of stay, infection rates and mortality rates

Ref.	Type of study	Study population	Outcomes
Wasiak et al[20], 2006	Cochrane analysis	-	No difference in all-cause mortality
			No difference in ICU length of stay
			No difference in adverse outcomes
Fuentes Padilla et al[21], 2019	Systematic review	-	No difference in mortality
			No difference in GI complications
Shahi et al [22], 2021	Retrospective review	132 pediatric burns patients	EEN has shorter length of ICU stay
			No difference in GI and infectious complications
Castanon et al[23], 2020	Retrospective RCT	324 geriatric burns patients with TBSA of 31%	EEN associated with lower mortality risk
			EEN had shorter length of ICU stay
Mosier et al[24], 2011	Retrospective cohort analysis	229 burns patients with TBSA of 46%	Early feeding associated with shorter ICU length of stay
			EEN had decreased wound infection rates
Yang et al[25], 2024	Systematic review	1066 severely burned patients	Decreased mortality in EEN
			EEN had less GI and infectious complications
			EEN had shorter length of stay

RCT: Randomized controlled trial; TBSA: Total body surface area; ICU: Intensive care unit; GI: Gastrointestinal; EEN: Early enteral nutrition.