Serotonin syndrome controversies: A need for consensus

Table 2 The Sternbach and Hunter criteria for serotonin syndrome

The Sternbach’s criteria[33]	Hunter criteria[6]
1. A history of serotonergic agent ingestions	1. A history of serotonergic agent ingestions
2. Exclusion of other aetiologies	2. Exclusion of other aetiologies
3. Any three of the followings	3. Any of the following combinations
(i) Mental status changes	(i) Spontaneous clonus
(ii) Agitation	(ii) Hyperreflexia and tremor
(iii) Myoclonus	(iii) Inducible clonus or ocular clonus plus any of followings
(iv) Fever
(v) Hyperreflexia	(a) Diaphoresis
(vi) Diaphoresis	(b) Agitation
(vii) Shivering	(c) Fever and rigidity
(viii) Tremor
(ix) Diarrhoea,
(x) Incoordination