Stress cardiomyopathy in critical care: A case series of 109 patients

Table 1 Patient baseline characteristics and presentation by unit

	Overall, n = 109	MSICU, (n = 49)	CCU, (n = 60)	P value1
Age (yr), mean (SD)	67.2 (14.2)	64.9 (14.4)	69 (13.7)	0.13
Female gender – n (%)	78 (71.6)	30 (61.2)	48 (80.0)	0.04
Race/Ethnicity – n (%)				0.37
White	30 (27.5)	17 (34.7)	13 (21.7)
Black	20 (18.4)	9 (18.4)	11 (18.3)
Hispanic	42 (38.5)	15 (30.6)	27 (45.0)
Other	17 (15.6)	8 (16.3)	9 (15.0)
Comorbidities – n (%)
Diabetes mellitus	40 (36.7)	19 (38.8)	21 (35)	0.68
Hypertension	65 (59.6)	23 (46.9)	42 (70)	0.01
Coronary disease	13 (11.9)	5 (10.2)	8 (13.3)	0.77
Heart failure	7 (6.4)	4 (8.2)	3 (5)	0.70
Arrhythmia	14 (12.8)	4 (8.2)	10 (16.7)	0.25
Asthma	16 (14.7)	6 (12.2)	10 (16.7)	0.52
COPD	13 (11.9)	6 (12.2)	7 (11.7)	0.93
Obesity	10 (9.2)	3 (6.1)	7 (11.7)	0.51
CKD	14 (12.8)	8 (16.3)	6 (10)	0.33
ESRD	3 (2.8)	1 (2)	2 (3.3)	1.00
Cancer	23 (21.1)	10 (20.4)	13 (21.7)	1.00
Cirrhosis	6 (5.5)	5 (10.2)	1 (1.7)	0.09
HIV	2 (1.8)	1 (2)	1 (1.7)	1.00
Social risk factors – n (%)
Alcohol use	25 (22.9)	13 (26.5)	12 (20)	0.42
Current smoker	15 (13.8)	4 (8.2)	11 (18.3)	0.17
Former smoker	36 (33)	21 (42.9)	15 (25)	0.05
Presenting symptoms- n (%)
Chest pain	35 (32.1)	8 (16.3)	27 (45)	0.001
SOB	55 (50.5)	23 (46.9)	32 (53.3)	0.51
Shock	41 (37.6)	29 (59.2)	12 (20)	< 0.001
Reason for unit admission- n (%)
Cardiac	44 (40.3)	0 (0.0)	44 (73.3)	< 0.001
Respiratory	14 (12.8)	9 (18.4)	5 (8.3)	0.54
Sepsis	24 (22.0)	19 (38.8)	5 (8.3)	< 0.001
GI	11 (10.0)	9 (18.4)	2 (3.3)	0.14
Neurological	7 (6.4)	6 (12.2)	1 (1.7)	0.04
Metabolic	4 (3.7)	3 (6.1)	1 (1.7)	0.32
Other	5 (4.6)	3 (6.1)	2 (3.3)	0.66

¹Corresponds to chi-square or Fisher’s exact test for association for categorical variables, Wilcoxon Mann-Whitney test for continuous variables. Data are summarized as mean (SD) or n (%), where n = available sample size. MSICU: Medical surgical intensive care unit; CCU: Coronary care unit; COPD: Chronic obstructive pulmonary disease; CKD: Chronic kidney disease; ESRD: End stage renal disease; HIV: Human immunodeficiency virus; SOB: Shortness of breath; GI: Gastrointestinal.