Retrospective analysis of anti-inflammatory therapies during the first wave of COVID-19 at a community hospital

Table 1 Coronavirus disease 2019 patients admitted to intensive care unit characteristics of survivors and non-survivors, n (%)

	Non-survivor (n = 167)	Survivor (n = 94)	P value	OR	95%CI
Age	71 (61, 82)	61 (62, 78)	0.011
Race (Caucasian)	89 (75)	40 (56)	0.007	2.37	1.27-4.40
BMI	29 (23, 34)	28 (24, 32)	0.49
Sex (male)	75 (70)	83 (53)	0.01	0.49	0.29-0.84
Diabetes	31 (29)	53 (34)	0.3	1.26	0.75-2.2
CHF	13 (12)	21 (14)	0.7	1.1	0.66 – 2.4
CAD	24 (29)	41 (27)	0.41	1.2	0.7-2.2
COPD	38 (23)	23 (30)	0.75	0.9	0.5-1.6
CKD	11 (10)	21 (17)	0.1	1.85	0.87-3.83
HTN	54 (51)	91 (59)	0.16	1.4	0.86-2.3
AKI	87 (52)	30 (32)	0.002	2.3	1.21-2.5
Mechanical ventilation	134 (80)	44 (47)	< 0.001	4.7	2.7-8.3
Hemodialysis	29 (18)	10 (11)	0.13	1.8	0.3-3.9
Neutrophils × 109/L	7.3 (4, 10)	7.8 (5.1, 13)	0.97
Lymphocytes	0.7 (0.5, 1.2)	0.9 (0.6, 1.6)	0.011
Neutrophil/lymphocyte	10 (6, 18)	7.5 (4, 14)	0.017
SCr (mg/dL)	1.2 (0.9, 1.9)	1.2 (0.8, 1.8)	0.49
Plts (× 109 /L)	230 (162, 310)	236 (182, 302)	0.27
Tbili (mg/dL)	0.5 (0.4, 0.8)	0.5 (0.4, 0.8)	0.65
SOFA admit	5 (3, 9)	4 (2, 6)	0.095
PaO2/FIO2	190 (76, 285)	232 (123, 307)	0.039
PaO2	68 (52, 116)	66 (48-112)	0.083
FIO2	1 (0.45, 1)	1 (0.96, 1)	0.12

OR: Odds ratio; CI: Confidence interval; CAD: Coronary artery disease; COPD: Chronic obstructive pulmonary disease; CKD: Chronic kidney disease; CHF: Congestive heart failure; AKI: Acute kidney injury; HD: Hemodialysis; tBili: Total bilirubin; Plts: Platelets INR: International normalized ratio. PaO₂/FiO₂: Partial pressure of oxygen/inspired concentration of oxygen ratio; SOFA: Sequential Organ Failure Assessment; BMI: Body mass index; SCr: Serum creatinine.