Multicentered prospective investigator initiated study to evaluate the clinical outcomes with extracorporeal cytokine adsorption device (CytoSorb®) in patients with sepsis and septic shock

doi:10.5492/wjccm.v10.i1.22

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Jan 9, 2021 (publication date) through May 10, 2024

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Crit Care Med. Jan 9, 2021; 10(1): 22-34
Published online Jan 9, 2021. doi: 10.5492/wjccm.v10.i1.22

Table 5 Change in vital parameters in survivors

Parameters	Survivor group		P value
	Pre CytoSorb^®therapy, mean ± SD	Post CytoSorb^®therapy, mean ± SD
Heart rate, beats/min	118.57 ± 19.8	103.07 ± 19.38	0.0065¹
MAP, mmHg	68.61 ± 9.62	79.42 ± 9.05	0.0001¹
GCS	9.86 ± 2.34	12.20 ± 1.47	0.0001¹
PaCO₂	43.32 ± 18.63	38.57 ± 11.66	0.2757
PaO₂/FiO₂	162.09 ± 82.99	161.20 ± 66.58	0.9704

¹Significant P value < 0.05.

All values are defined as mean ± SD. FiO2: Fraction of inspiration O₂; GCS: Glasgow coma scale; MAP: Mean arterial pressure; PaCO₂: Partial pressure of carbon dioxide; PaO₂: Alveolar oxygen partial pressure; SD: Standard deviation.

Citation: Paul R, Sathe P, Kumar RS, Prasad S, Aleem M, Sakhalvalkar P. Multicentered prospective investigator initiated study to evaluate the clinical outcomes with extracorporeal cytokine adsorption device (CytoSorb^®) in patients with sepsis and septic shock. World J Crit Care Med 2021; 10(1): 22-34
URL: https://www.wjgnet.com/2220-3141/full/v10/i1/22.htm
DOI: https://dx.doi.org/10.5492/wjccm.v10.i1.22