Multicentered prospective investigator initiated study to evaluate the clinical outcomes with extracorporeal cytokine adsorption device (CytoSorb®) in patients with sepsis and septic shock

Table 3 Change in laboratory parameters for survivors

Parameters	Pre CytoSorb® therapy	Post CytoSorb® therapy	P value
Hb, g/dL	10.01 ± 2.20	9.28 ± 1.53	0.1830
HCT, %	29.74 ± 8.4	25.75 ± 7.67	0.0909
Leucocytes, µL	16724 ± 5425	11215 ± 3317	0.00011
Platelets, cells/mm3	139256 ± 88029	181203 ± 181381	0.2938
S. Creatinine, mg/dL	3.13 ± 1.92	2.08 ± 1.02	0.01901
S. Lactate, mmol/L	4.75 ± 2.77	2.88 ± 2.39	0.01201
SGOT, U/L	488.44 ± 1570.42	369.95 ± 1134.74	0.7661
SGPT, U/L	192.72 ± 298.99	145.90 ± 236.97	0.5503
BUN, mg/dL	76.21 ± 61.88	62.39 ± 52.28	0.4076
Bilirubin, mg/dL	9.91 ± 36.77	8.35 ± 31.36	0.8730
Sodium, mmol/L	134.38 ± 25.69	134.32 ± 6.20	0.9908
Potassium, mmol/L	3.98 ± 0.95	3.73 ± 1.05	0.3723
Albumin, g/L	2.65 ± 0.93	2.71 ± 0.95	0.8261
Arterial pH	7.35 ± 0.100	7.36 ± 0.105	0.7291
Bicarbonate	24.89 ± 10.71	24.75 ± 9.21	0.9599

¹Significant value P < 0.05, all values are defined as mean ± SD.

BUN: Blood urea nitrogen; Hb: Hemoglobin; HCT: Hematocrit; SD: Standard deviation; SGOT: Serum glutamic oxaloacetic transaminase; SGPT: Serum glutamic-pyruvic transaminase.