Original Article
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World J Clin Urol. Mar 24, 2014; 3(1): 47-53
Published online Mar 24, 2014. doi: 10.5410/wjcu.v3.i1.47
Development of a nomogram for predicting a positive repeat prostate biopsy
Ryo Iseki, Makoto Ohori, Alice Piccorelli, Changhong Yu, Annie Piccorelli, Yoshio Ohno, Masaaki Tachibana, Michael W Kattan
Ryo Iseki, Makoto Ohori, Yoshio Ohno, Masaaki Tachibana, Department of Urology, Tokyo Medical University, Shinjuku, Tokyo 160-0023, Japan
Alice Piccorelli, Changhong Yu, Annie Piccorelli, Michael W Kattan, Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland Clinic Foundation, Cleveland, OH 44195, United States
Author contributions: All the authors contributed to this work.
Correspondence to: Ryo Iseki, MD, Department of Urology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku, Tokyo 160-0023, Japan. iseki@tokyo-med.ac.jp
Telephone: +81-3-33426111 Fax: +81-3-33444813
Received: September 27, 2013
Revised: November 22, 2013
Accepted: December 13, 2013
Published online: March 24, 2014
Core Tip

Core tip: Although prostate cancer is found in about 30% of patients at the initial biopsy session, there is a need to identify those with a negative result but who are at high risk. Although individual risk factors have been found to be associated with cancer, patient counseling requires the integration of multiple risk factors to obtain a prediction for the individual. We developed a nomogram that predicts a positive biopsy after a previous negative biopsy session. It provides a wide range of probabilities for cancer and may help clinical judgment of whether to do a repeat prostate biopsy.