Clinical characteristics of community-acquired pneumonia in children caused by mycoplasma pneumoniae with or without myocardial damage: A single-center retrospective study

Table 1 Gender distribution

Gender	Frequency	Percentage
Female	195	47.68
Male	214	52.32
Total	409	100.00

Table 2 Age distribution of community-acquired pneumonia in hospitalized children with mycoplasma pneumoniae pneumonia categorized as mild and severe, n (%)

Age group	Total	Mild MPP	Severe MPP
< 5 yr	317	232 (77.6)	85 (77.3)
≥ 5 yr	92	67 (22.4)	25 (22.7)
Total	409	299	110

MPP: Mycoplasma pneumoniae pneumonia.

Table 3 Seasonality of mycoplasma pneumoniae pneumonia, n (%)

Season	Mild MPP	Severe MPP
Winter	102 (34.10)	41 (37.30)
Spring	80 (26.80)	28 (25.50)
Summer	28 (9.40)	11 (10.00)
Autumn	89 (29.80)	30 (27.30)

MPP: Mycoplasma pneumoniae pneumonia.

Table 4 Clinical characteristics and laboratory investigations of hospitalized children with community-acquired pneumonia caused by mycoplasma pneumonia were compared between the severe and mild case groups

Parameters	Mild MPP (n = 299)	Severe MPP (n = 110)	Z	P value
Gender	1.48 ± 0.501	1.45 ± 0.500	0.54	0.58
Age (yr)	3.59 ± 2.63	3.40 ± 2.16	0.69	0.49
Fever (℃)	38.73 ± 0.86	38.71 ± 0.83	0.163	0.87
Duration of fever	4.27 ± 3.37	5.76 ± 5.39	-2.72	0.007
Duration of cough	5.98 ± 6.9	11.4 ± 10.33	-5.103	< 0.001
WBC (109/L)	8.98 ± 4.77	9.34 ± 4.23	-0.691	0.49
Lymphocyte (%)	35.87 ± 14.04	38.93 ± 18.29	-1.59	0.114
Neutrophil (%)	54.48 ± 15.46	49.98 ± 20.28	2.113	0.036
Neutrophil to lymphocyte ratio	2.06 ± 1.702	2.046 ± 2.20	0.078	0.938
CRP (mg/L)	12.59 ± 19.24	10.48 ± 17.82	1	0.318
hsCRP (mg/L)	6.1 ± 5.84	8.35 ± 7.5	-2.834	0.005
PCT (ng/mL)	0.42 ± 0.93	0.76 ± 3.15	-1.097	0.27
Alanine transaminase (U/L)	15.95 ± 8.42	24.97 ± 37.32	-2.511	0.013
Aspartate aminotransferase (U/L)	32.25 ± 20.31	41.37 ± 30.11	-2.939	0.004
Creatine kinase (U/L)	97.3 ± 110.38	101.4 ± 83	-0.354	0.724
Lactate dehydrogenase (U/L)	286.55 ± 69.12	317.55 ± 93.77	-3.633	< 0.001

CRP: C-reactive protein; hsCRP: C-reactive protein; PCT: Procalcitonin; WBC: White blood cell.

Table 5 Auscultatory and myocardial damage findings among the mild and severe mycoplasma pneumoniae pneumonia cases, n (%)

Parameters		Mild MPP	Severe MPP	χ2	P value
1 Auscultation	Crackles	37 (12.40)	23 (20.90)	11.915	0.008
	Normal	141 (47.20)	35 (31.80)
	Wet rales	7 (2.30)	7 (6.40)
	Wheezing	114 (38.10)	45 (40.90)
2 Myocardial damage	Yes	0 (0.0)	52 (47.30)	157.078	< 0.001
	No	299 (100)	58 (52.70)

MPP: Mycoplasma pneumoniae pneumonia.