Systematic Reviews
Copyright ©The Author(s) 2016.
World J Clin Pediatr. Nov 8, 2016; 5(4): 397-403
Published online Nov 8, 2016. doi: 10.5409/wjcp.v5.i4.397
Table 1 Levels of evidence in medical research
Level of evidenceStudy design
Level ISystematic review (with homogeneity) of RCTs
RCT with statistically significant difference or narrow confidence intervals
Level IILow quality RCT (e.g., < 80% follow-up)
Cohort study or other Prospective comparative study
Systematic review of cohort studies
Level IIICase-control study or other Retrospective comparative study
Systematic review of case-control studies
Level IVCase series
Poor quality case-control studies
Level VExpert opinion
Narrative reviews