Resuscitation of extremely preterm infants - controversies and current evidence

Table 2 Overview of the results of the studies comparing continuous positive airway pressure and invasive ventilation

Ref.	Total number	Gestational age (GA) in wk	Death or BPDCPAP	Death or BPDnon CPAP	Death or BPD relative risk(95%CI)	Days needing mechanical ventilationCPAP	Days needing mechanical ventilationnon CPAP	Days needing mechanical ventilationP value
Morley et al[51]	610	25-28	108/307	118/303	0.9 (0.73-1.11)	0-11	11-14	< 0.001
SUPPORT[52]	1316	24-27	323/663	353/653	0.9 (0.81-1.00)	2-32	2-36	0.01
Sandri et al[54]	208	25-28	53/103	32/105	1.01 (0.7-1.57)	1-14	1-18	< 0.01
Dunn et al[53]	648	26-29	68/223	138/425	0.94 (0.74-1.19)	1-8	1-10	0.01

Infants randomised to prophylactic surfactant group and intubate, surfactant, or extubate group were combined in the intubation group. CPAP: Continuous positive airway pressure; BPD: Bronchopulmonary dysplasia.