Use of corticosteroids during acute phase of Kawasaki disease

Table 2 Risk scoring systems for the selection of patients expected to have unresponsiveness to initial intravenous immunoglobulin treatment

	Cut-off	Points
Kobayashi score (≥ 4-5 points)[51,54,55]
Age	≤ 12 mo	1
Days of illness at initial treatment	≤ 4	2
Platelet count	≤ 300 × 103/mm3	1
Neutrophil	≥ 80%	2
CRP	≥ 10 mg/dL	1
AST	≥ 100 IU/L	2
Sodium	≤ 133 mmol/L	2
Egami score (≥ 3 points)[52]
Age	≤ 6 mo	1
Days of illness at initial treatment	≤ 4	1
Platelet count	≤ 300 × 103/mm3	1
CRP	≥ 8 mg/dL	1
ALT	≥ 80 IU/L	2
Sano score (≥ 2 points)[53]
CRP	≥ 7 mg/dL	1
AST	≥ 200 IU/L	1
Total bilirubin	≥ 0.9 mg/dL	1

IVIG: Intravenous immunoglobulin; CRP: C-reactive protein; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.