Acute encephalitis and encephalopathy associated with human parvovirus B19 infection in children

Table 3 Laboratory data and treatment of children with B19 encephalitis and encephalopathy

Case	Anemia	Serum B19 markers			CSF B19 markers			CSF		IVIG
No.		IgM	IgG	DNA	IgM	IgG	DNA	Pleocytosis	Increased protein	and/or steroids
1	-							+	-	-
2	-							-	+	-
3	-	+	+	+			-	+	+	-
4		-	-	-	-	-	+	-		IVIG
5					+	-	-	-	-	-
6	+				-	-	+	-	-	-
7	-				-	-	+			-
8	+	+	-	+	-	-	+			-
9	-						+			-
10	-						+	-		-
11	-						+	+		-
12	+	+	-	+	+	-	+			-
13	+	-	-	-	-	-	+			-
14	+	+	+	+				+		-
15	+	+	+	+				+		-
16	+	+	+	+				+		-
17	+	+	+	+				+		-
18	-	+	-		-	-		+	+	IVIG and steroids
19	+	+		+				+	+	-
20	-	-	-	+	-	-	+	+	-	IVIG and steroids
21	-	+	+	+			+	+	+	Steroids
22	+	+		+			+	-		-
23	-	+	+	+			+	-	+	-
24	+	+	+	+			+	-	+	-
25	-	+	+	+	-	-	+	+	+	-
26	+	+	+	-	-	-		-	-	Steroids
27	+			+			+	-	-	-
28	-	+	+				+	-	-	IVIG and steroids
29	-	+	-							-
30	+	+	-					+	-	-
31	+	-	+	+			+	-	-	Steroids
32	+							-	-	IVIG
33	+							-	-	IVIG
34	+	+	+	+			+	-	-	-

IVIG: Intravenous immunoglobulin; CSF: Cerebrospinal fluid.