Acute encephalitis and encephalopathy associated with human parvovirus B19 infection in children

Table 1 Basic characteristics of children with B19 encephalitis and encephalopathy

Case No.	Ref.	Age	Gender	Diagnosis	Underlying disorders	Immunodeficiency
1	[16]	8 yr	M	Encephalitis		-
2	[17]	9 mo	M	Encephalitis		-
3	[19,20]	5 yr	F	Encephalitis		-
4	[23,24]	2 mo	F	Encephalitis		-
5	[23,24]	2 yr	M	Encephalitis	Acute lymphocytic leukemia	+
6	[23,24]	2 yr	F	Encephalitis		-
7	[23,24]	6 yr	F	Encephalitis	Cockayne syndrome	+
8	[23,24]	9 yr	M	Encephalitis		-
9	[23,24]	13 yr	F	Encephalitis	Crigler-Najar syndrome	-
10	[23,34]	13 yr	M	Encephalitis		-
11	[23,34]	15 yr	F	Encephalitis		-
12	[23,24]	1 d	F	Encephalitis	Necrotizing enterocolitis Patent ductus arteriosus Respiratory distress syndrome	+
13	[23,24]	1 d	F	Encephalitis	Ventricular septal defect Atrial septal defect Patent ductus arteriosus Turner syndrome Obstructive jaundice	+
14	[25]	8 yr	F	Encephalitis	Sickle cell disease Nephrotic syndrome	+
15	[25]	8 yr	M	Encephalitis	Sickle cell disease Nephrotic syndrome	+
16	[25]	12 yr	F	Encephalitis	Sickle cell disease Aplastic crisis	+
17	[25]	14 yr	M	Encephalitis	Sickle cell disease Aplastic crisis	+
18	[27]	10 yr	F	Encephalitis		-
19	[28]	9 yr	M	Encephalitis	Nephropathic cystinosis Renal transplant	+
20	[30]	4 yr	F	Encephalitis		-
21	[31]	5 yr	F	Encephalitis and cerebellitis		-
22	[18]	8 yr	F	Encephalopathy		-
23	[19]	5 yr	F	Encephalopathy		-
24	[21]	5 yr	M	Encephalopathy		-
25	[22]	4 yr	M	Encephalopathy	Prader-Willi syndrome	-
26	[26]	13 yr	F	Encephalopathy	Sβ + thalassemia	+
27	[9]	8 yr	F	Chorea encephalopathy		-
28	[10]	1 yr	M	Chorea encephalopathy		-
29	[11]	1 yr	M	Chorea encephalopathy		-
30	[11]	1 yr	F	Chorea encephalopathy		-
31	[29]	9 yr	F	MERS	Hereditary spherocytosis	-
32	[12]	11 yr	M	MERS	Hereditary spherocytosis	-
33	[12]	10 yr	M	MERS	Hereditary spherocytosis	-
34	[13]	9 yr	F	PRES	Acute glomerulonephritis	-

MERS: Clinically mild encephalitis/encephalopathy with reversible splenial lesion; PRES: Posterior reversible encephalopathy syndrome; F: Female; M: Male.