Tramadol use in pediatric sickle cell disease patients with vaso-occlusive crisis

Table 2 Independent admissions statistical analysis

	Morphine (n = 18)	Morphine + tramadol (n = 12)	P-value1
Morphine requirement (mg/kg per day), mean ± SD	0.65 ± 0.35	0.58 ± 0.48	0.31
Pain score, median (range)	5 (0-8)	6.75 (3-9)	0.07
PCA duration (d), median (range)	4.5 (0-13)	5 (3-14)	0.33
LOS (d), median (range)	7 (4-14)	7.5 (3-17)	0.85
Respiratory rate, mean (range)	21 (14-29)	19 (16-23)	0.28
Polyethylene glycol dose (gm/kg per day), mean (range)	0.6 (0-1.66)	0.5 (0-1.12)	0.64

¹P-value calculated using Wilcoxon Rank Sum test. PCA: Patient-controlled analgesia; LOS: Length of stay.