Early lactase enzyme supplementation: Efficacy to promote growth and feeding tolerance in preterm infants: A randomized controlled trial

doi:10.5409/wjcp.124805

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Dec 9, 2026; 15(4): 124805
Published online Dec 9, 2026. doi: 10.5409/wjcp.124805

Table 2 Laboratory findings between the studied groups at study entry and at the 2^nd week, mean ± SD

Variable	Intervention group (n = 55)	Control group (n = 54)	P value
Hb (g/dL)
At study entry	16.55 ± 2.7	15.8 ± 2.4	0.131
At 2^nd week	12.95 ± 2.16	12.89 ± 2.4	0.895
TLC (× 10³/mL)
At study entry	11.0 ± 4.6	10.6 ± 4.94	0.691
At 2^nd week	11.94 ± 5.16	14.2 ± 6.759	0.053
PLT (× 10³/mL)
At study entry	255.6 ± 87.82	256.9 ± 104.4	0.956
At 2^nd week	282.7 ± 139.1	296.3 ± 130.2	0.599
CRP (mg/L)
At study entry	3.1 ± 2.5	3.27 ± 1.98	0.786
At 2^nd week	10.3 ± 30.2	7.1 ± 15.51	0.486

Hb: Hemoglobin; TLC: Total leukocytic count; PLT: Platelets; CRP: C-reactive protein.

Full Size Table

Citation: Morsi WEMA, Eskander AE, Mostafa MG, Ezz ElDin Z, Abdel Maksoud FA, Elrefaee A. Early lactase enzyme supplementation: Efficacy to promote growth and feeding tolerance in preterm infants: A randomized controlled trial. World J Clin Pediatr 2026; 15(4): 124805
URL: https://www.wjgnet.com/2219-2808/full/v15/i4/124805.htm
DOI: https://dx.doi.org/10.5409/wjcp.124805

Morsi WEMA, Eskander AE, Mostafa MG, Ezz ElDin Z, Abdel Maksoud FA, Elrefaee A. Early lactase enzyme supplementation: Efficacy to promote growth and feeding tolerance in preterm infants: A randomized controlled trial. World J Clin Pediatr 2026; 15(4): 124805 [DOI: 10.5409/wjcp.124805]

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