Development of a clinical prediction score for recurrent wheezing following acute lower respiratory tract infection in children

doi:10.5409/wjcp.123752

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Dec 9, 2026; 15(4): 123752
Published online Dec 9, 2026. doi: 10.5409/wjcp.123752

Table 4 Performance of the clinical score and risk classification for recurrent wheezing

Score (points)	Risk classification	PPV (95%CI)	NPV (95%CI)	Sensitivity (95%CI)	Specificity (95%CI)	PLR (95%CI)	NLR (95%CI)
0-1	Low	16.04% (11.88-21.31)	41.94% (28.36-56.85)	48.57% (31.38-66.01)	12.75% (6.96-20.81)	0.56 (0.39-0.79)	4.04 (2.21-7.36)
2-3	Moderate	48.0% (31.77-64.66)	79.46% (75.07-83.25)	34.29% (19.13-52.21)	87.25% (79.19-93.04)	2.69 (1.36-5.33)	0.75 (0.59-0.97)
4-9	High	100% (54.07-100)	77.86% (75.16-80.35)	17.14% (6.56-33.65)	100% (96.45-100)	∞ (due to 100% specificity)	0.83 (0.71-0.96)

PPV: Positive predictive value; CI: Confidence interval; NPV: Negative predictive value; PLR: Positive likelihood ratio; NLR: Negative likelihood ratio.

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Citation: Dokkham P, Kiatvitchukul T, Jeephet K, Srisingh K. Development of a clinical prediction score for recurrent wheezing following acute lower respiratory tract infection in children. World J Clin Pediatr 2026; 15(4): 123752
URL: https://www.wjgnet.com/2219-2808/full/v15/i4/123752.htm
DOI: https://dx.doi.org/10.5409/wjcp.123752

Dokkham P, Kiatvitchukul T, Jeephet K, Srisingh K. Development of a clinical prediction score for recurrent wheezing following acute lower respiratory tract infection in children. World J Clin Pediatr 2026; 15(4): 123752 [DOI: 10.5409/wjcp.123752]

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