Development of a clinical prediction score for recurrent wheezing following acute lower respiratory tract infection in children

doi:10.5409/wjcp.123752

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Dec 9, 2026; 15(4): 123752
Published online Dec 9, 2026. doi: 10.5409/wjcp.123752

Table 2 Univariable logistic regression analysis of risk factors for recurrent wheezing

Risk factor	Odd ratio	95%CI	P value
Thalassemia disease	3.59	1.19-10.83	0.023
Allergic rhinitis	2.96	1.35-6.49	0.007
Food or drug allergy	1.84	0.68-5.01	0.230
Maternal smoking during pregnancy	1.71	0.68-4.31	0.255
Passive smoke exposure	1.52	0.75-3.10	0.249
First-degree related family history of asthma	4.74	1.32-17.05	0.017
Day care attendance	1.58	0.83-3.00	0.166
Multiple LRTIs	5.54	2.92-10.49	< 0.001
Eosinophilia¹	8.48	2.42-29.74	0.001
RSV infection	0.76	0.41-1.42	0.396

¹Eosinophilia was analyzed in 137 participants with available eosinophil count data; all other variables were analyzed in the full cohort of 280 participants.

LRTI: Lower respiratory tract infection; RSV: Respiratory syncytial virus; CI: Confidence interval.

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Citation: Dokkham P, Kiatvitchukul T, Jeephet K, Srisingh K. Development of a clinical prediction score for recurrent wheezing following acute lower respiratory tract infection in children. World J Clin Pediatr 2026; 15(4): 123752
URL: https://www.wjgnet.com/2219-2808/full/v15/i4/123752.htm
DOI: https://dx.doi.org/10.5409/wjcp.123752

Dokkham P, Kiatvitchukul T, Jeephet K, Srisingh K. Development of a clinical prediction score for recurrent wheezing following acute lower respiratory tract infection in children. World J Clin Pediatr 2026; 15(4): 123752 [DOI: 10.5409/wjcp.123752]

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