Does Takayasu arteritis differ between children and adolescents? Insights from a Russian multicenter cohort

Table 1 Demographic and baseline characteristics of the total cohort and stratified by age group (< 10 years vs ≥ 10 years), n (%)

Characteristic	Total cohort (n = 79)	< 10 years (n = 25)	≥ 10 years (n = 54)	P value
Age at onset, years, median (IQR)	11.0 (8.0-14.0)	7.0 (5.0-8.5)	13.0 (11.0-14.0)	< 0.001
Female sex	62 (78.5)	15 (60.0)	47 (87.0)	0.016
Diagnostic delay, months, median (IQR)	8.0 (2.0-17.5)	10.0 (2,0-24.0)	7.0 (2.0-12.0)	0.209
Follow-up duration, months, mean ± SD	28.0 ± 22.0	35.8 ± 28.4	24.6 ± 19.6	0.088
Surgical intervention at diagnosis	12 (15.2)	8 (32.0)	4 (7.4)	0.008
ITAS.A at onset, mean ± SD	11.0 ± 4.6	8.9 ± 4.3	12.0 ± 4.4	0.005
ITAS 2010 at onset, median (IQR)	7.0 (5.0-12.5)	5.0 (3.0-8.0)	7.0 (5.0-9.0)	0.061
ESR at onset, mm/hour, mean ± SD	47.8 ± 24.9	37.5 ± 19.5	52.7 ± 25.8	0.012
CRP at onset, mg/L, median (IQR)	35.5 (11.8-90.2)	17.0 (5.0-36.0)	47.0 (15.0-100.2)	0.003

IQR: Interquartile range; ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein.