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Copyright: ©Author(s) 2026.
World J Clin Pediatr. Dec 9, 2026; 15(4): 120091
Published online Dec 9, 2026. doi: 10.5409/wjcp.120091
Table 6 Sleep parameters, neurobiological mechanisms, and cognitive outcomes in school-age children
Sleep parameter
Key neurobiological mechanisms
Cognitive/executive domains affected
Representative interventions
Total sleep durationSynaptic homeostasis; energy restoration; prefrontal cortex efficiencyAttention, working memory, processing speed, and inhibitory controlAge-appropriate sleep schedules; parent-guided bedtime routines
Sleep quality (continuity, fragmentation)Stable neural oscillations; efficient hippocampal-cortical communicationLearning efficiency, executive control, sustained attentionSleep hygiene education: Reducing nighttime awakenings
Slow-wave sleep (non-rapid eye movement stage 3)Memory consolidation; synaptic downscaling; cortical plasticityDeclarative memory, learning retention, executive integrationConsistent sleep timing; minimizing evening arousal and caffeine
Rapid eye movement sleepEmotional memory processing; procedural learning; cognitive flexibilityCognitive flexibility, emotional regulation, and problem-solvingRegular sleep-wake cycles; limiting screen exposure before bedtime
Sleep timing/circadian alignmentSynchronization of circadian clocks; optimal melatonin signalingAttention, academic performance, and executive efficiencyFixed wake times, morning light exposure, and delayed evening screen use
Sleep regularity (weekday-weekend consistency)Circadian rhythm stability; neuroendocrine regulationSustained attention; behavioral regulation; metacognitionConsistent bedtimes; limiting “social jet lag”
Sleep hygiene behaviorsReduced cognitive arousal, autonomic balance, and stress modulationExecutive control; emotional regulation; learning readinessScreen-free bedtime routines; calming pre-sleep activities
Sleep disruption (chronic deprivation)Prefrontal hypoactivation; increased cortisol; neuroinflammationInhibitory control deficits, impulsivity, and attention lapsesBehavioral sleep interventions; school-based sleep education


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