Association of Helicobacter pylori infection with insulin resistance, tumor necrosis factor-alpha, and dyslipidemia in obese children with metabolic syndrome

Table 5 Pearson correlation between homeostasis model assessment of insulin resistance and study variables within each group

Variable	r (group Ia)	P value (Ia)	r (group Ib)	P value (Ib)
Age (years)	0.023	0.895	-0.228	0.188
Standardized BMI value	0.293	0.088	0.889	< 0.001a
ALT (U/L)	-0.076	0.663	-0.196	0.260
AST (U/L)	-0.237	0.170	0.038	0.827
Total cholesterol (mg/dL)	0.075	0.670	0.206	0.235
Triglycerides (mg/dL)	-0.148	0.397	0.080	0.648
LDL-C (mg/dL)	0.044	0.800	-0.028	0.873
HDL-C (mg/dL)	0.113	0.518	0.102	0.559
Fasting plasma glucose (mg/dL)	0.716	< 0.001a	0.401	0.017a
HbA1c (%)	0.115	0.511	0.653	< 0.001a
2-hour postprandial glucose (mg/dL)	0.119	0.494	0.071	0.687
Fasting insulin (μIU/mL)	0.833	< 0.001a	0.788	< 0.001a
TNF-α (assay units)	0.185	0.288	0.896	< 0.001a
Adiponectin (assay units)	-0.234	0.176	-0.080	0.648
Leptin (assay units)	0.149	0.394	0.259	0.132

^aP < 0.05.

R values represent Pearson correlation coefficients between homeostasis model assessment of insulin resistance (calculated as fasting insulin × fasting glucose/405) and the listed variables within each group. Group Ia: Helicobacter pylori (H. pylori)-negative; Group Ib: H. pylori-positive. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol; HbA1c: Glycated hemoglobin; BMI: Body mass index; TNF-α: Tumor necrosis factor-alpha.