Association of Helicobacter pylori infection with insulin resistance, tumor necrosis factor-alpha, and dyslipidemia in obese children with metabolic syndrome

doi:10.5409/wjcp.v15.i3.121926

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World Journal of Clinical Pediatrics

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2219-2808

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Sep 9, 2026; 15(3): 121926
Published online Sep 9, 2026. doi: 10.5409/wjcp.v15.i3.121926

Table 3 Tumor necrosis factor-alpha, adiponectin, and leptin among the studied groups

Variable	*Group Ia (H. pylori-negative) (n = 35)*	*Group Ib (H. pylori-positive) (n = 35)*	P value
TNF-α, median (IQR)	6.23 (4.04-6.76)	7.13 (5.91-8.68)	0.011^a
Adiponectin, median (IQR)	7.57 (3.56-10.69)	8.74 (4.87-10.71)	0.647
Leptin, median (IQR)	12.86 (9.07-20.21)	13.97 (6.09-18.17)	0.756

^aP < 0.05.

Data are presented as median (interquartile range). P values were calculated using the Mann-Whitney U test. Units are as reported by the assay kits. TNF-α: Tumor necrosis factor-alpha; IQR: Interquartile range; H. pylori: Helicobacter pylori.

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Citation: Ibrahim Elbakry NM, Hemeda MS, Mostafa Mohamed Ahmed A, Adel Zaky H, Gamil AN, Arafat Abd Elmoaty AE, M Khafagi M, Mohamed Alkabeer A, Abd Elaziz Alsaid A, A Elhagary A, Mohammed Aboassy W, Nabil Gamil Mohammed A. Association of Helicobacter pylori infection with insulin resistance, tumor necrosis factor-alpha, and dyslipidemia in obese children with metabolic syndrome. World J Clin Pediatr 2026; 15(3): 121926
URL: https://www.wjgnet.com/2219-2808/full/v15/i3/121926.htm
DOI: https://dx.doi.org/10.5409/wjcp.v15.i3.121926

Ibrahim Elbakry NM, Hemeda MS, Mostafa Mohamed Ahmed A, Adel Zaky H, Gamil AN, Arafat Abd Elmoaty AE, M Khafagi M, Mohamed Alkabeer A, Abd Elaziz Alsaid A, A Elhagary A, Mohammed Aboassy W, Nabil Gamil Mohammed A. Association of Helicobacter pylori infection with insulin resistance, tumor necrosis factor-alpha, and dyslipidemia in obese children with metabolic syndrome. World J Clin Pediatr 2026; 15(3): 121926 [DOI: 10.5409/wjcp.v15.i3.121926]

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