Antibiotic stewardship in the context of management of early onset neonatal sepsis-an evolving paradigm shift

Table 1 Grading of evidence for included references using the Oxford Centre for Evidence-Based Medicine 2011 guidance

Ref.	Design	Level
[1]	Guideline	5
[2]	Guideline	5
[3]	Guideline	5
[4]	Cohort (model derivation)	2b
[5]	Narrative review	5
[6]	Cohort (surveillance)	2b
[7]	Cohort	2b
[8]	Implementation study	2b
[9]	Cohort	2b
[10]	Retrospective comparison	2b
[11]	Observational comparison	2b
[12]	Retrospective cohort	2b
[13]	Implementation study	2b
[14]	Multinational cohort	2b
[15]	Narrative article	5
[16]	Cohort	2b
[17]	Cohort	2b
[18]	Cohort	2b
[19]	Cohort	2b
[20]	Cross-sectional	4
[21]	Cohort	2b
[22]	Case control	3b
[23]	Review	5
[24]	Cohort (metagenomics)	2b
[25]	Cohort	2b
[26]	Cohort	2b
[27]	Cross-sectional	4
[28]	Economic model	-
[29]	Guideline	5
[30]	Cohort	2b
[31]	Guideline	5
[32]	Review	5
[33]	Cohort	2b
[34]	Multicentre cohort	2b
[35]	Observational study	2b
[36]	Systematic review + meta-analysis	1a
[37]	Cluster randomised controlled trial	1b
[38]	Systematic review + meta-analysis	1a
[39]	Review	5
[40]	Cohort	2b
[41]	Prospective observational implementation study	2b
[42]	Population cohort	2b
[43]	Population cohort	2b
[44]	Observational study	2b