Modality matters: Effect of dialysis modality on soluble intercellular adhesion molecule-1 in children on regular hemodialysis

doi:10.5409/wjcp.120090

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World Journal of Clinical Pediatrics

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2219-2808

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World J Clin Pediatr. Sep 9, 2026; 15(3): 120090
Published online Sep 9, 2026. doi: 10.5409/wjcp.120090

Table 2 Comparisons of serum intercellular adhesion molecule-1 levels

Cases		P value	Mean difference (95%CI)
Pre-session sICAM-1	LFHD vs HFHD	0.058¹	378.9² (-10.1-864.6)
	LFHD vs OL-HDF	0.051¹	737.7² (100.9-1449.0)
	HFHD vs OL-HDF	0.751¹	13.3² (-364.2-812.4)
Post-session cICAM-1	LFHD vs HFHD	< 0.001¹	-1655.6² (-2633.7 to -1088.0)
	LFHD vs OL-HDF	< 0.001¹	-1727.2² (-2782.8 to -1188.8)
	HFHD vs OL-HDF	0.011¹	-84.1² (-173.7 to -25.3)
Pre-session vs post-session cICAM-1	LFHD	0.002¹	871.5² (373.2-1749.9)
	HFHD	< 0.001¹	-1087.1² (-1439.5 to -755.6)
	OL-HDF	< 0.001¹	-1372.9² (-2143.8 to -786.9)

¹Wilcoxon signed ranks test.

²Hodges-Lehman median difference estimate.

sICAM-1: Soluble intercellular adhesion molecule-1; cICAM-1: Corrected intercellular adhesion molecule-1; LFHD: Low flux hemodialysis; HFHD: High flux hemodialysis; OL-HDF: Online hemodiafiltration; CI: Confidence interval.

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Citation: Kasem MF, Said RM, Dahshan DR, Elhadedy SH, Mohammed NR, Hashem NU. Modality matters: Effect of dialysis modality on soluble intercellular adhesion molecule-1 in children on regular hemodialysis. World J Clin Pediatr 2026; 15(3): 120090
URL: https://www.wjgnet.com/2219-2808/full/v15/i3/120090.htm
DOI: https://dx.doi.org/10.5409/wjcp.120090

Kasem MF, Said RM, Dahshan DR, Elhadedy SH, Mohammed NR, Hashem NU. Modality matters: Effect of dialysis modality on soluble intercellular adhesion molecule-1 in children on regular hemodialysis. World J Clin Pediatr 2026; 15(3): 120090 [DOI: 10.5409/wjcp.120090]

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