Transforming central line associated blood stream infection prevention in neonates: Results from a multimodal quality improvement initiative

doi:10.5409/wjcp.118413

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Sep 9, 2026; 15(3): 118413
Published online Sep 9, 2026. doi: 10.5409/wjcp.118413

Table 1 Demographics of study population, n (%)

Characteristics	Pre-intervention period (6 months)	Implementation period (12 months)	Sustainability period (18 months)
Total number of admissions	457	683	1218
No. of ELBW	46 (10)	77 (11.2)	160 (13.1)
Central line days	1249	1816	4145
No. of CLABSI cases	8	2	4
CLABSI rates/1000 central line days	6.4	1.1	0.96
Compliance to hand hygiene (%)	97.9%	98.1%	97.7%
Compliance to insertion bundle (%)	-	100%	97%
Compliance to maintenance bundle checklist (%)	-	Nurses 86%	Nurses 94%
Compliance to maintenance bundle checklist (%)	-	Doctors 82%	Doctors 93%
Compliance to nurses education (% staff coverage)	-	62%	81%

ELBW: Extremely low birth weight; CLABSI: Central line associated blood stream infection.

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Citation: Pillai A, Kabra N, Nayak A, Bhanushali M, Balasubramanian H, Shivananda S. Transforming central line associated blood stream infection prevention in neonates: Results from a multimodal quality improvement initiative. World J Clin Pediatr 2026; 15(3): 118413
URL: https://www.wjgnet.com/2219-2808/full/v15/i3/118413.htm
DOI: https://dx.doi.org/10.5409/wjcp.118413

Pillai A, Kabra N, Nayak A, Bhanushali M, Balasubramanian H, Shivananda S. Transforming central line associated blood stream infection prevention in neonates: Results from a multimodal quality improvement initiative. World J Clin Pediatr 2026; 15(3): 118413 [PMID: 42625981 DOI: 10.5409/wjcp.118413]

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