Study on intravenous immunoglobulin use in a pediatric intensive care unit of a tertiary care center

doi:10.5409/wjcp.v15.i2.118421

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Jun 9, 2026; 15(2): 118421
Published online Jun 9, 2026. doi: 10.5409/wjcp.v15.i2.118421

Table 3 Dose of intravenous immunoglobulin used in diseases, frequency and survival, n (%)

Dose of IVIG (g/kg)	Indications	Received IVIG	Survived
0.5	PID	2	2 (100)
1	AES, FIRES, Dengue, adenovirus, mycoplasma, HLH, PID, KD, myocarditis	105	61 (58.1)
2	AES, ADEM, ALERD, ANEC, GBS, MG, autoimmune encephalitis, Dengue, HLH, AIHA, myocarditis, KD, MIS-C	339	282 (83.2)
4	Guillain-Barré syndrome	9	8 (89)

IVIG: Intravenous immunoglobulin; PID: Primary immunodeficiency; AES: Acute encephalitis syndrome; FIRES: Febrile infection related epilepsy syndrome; HLH: Hemophagocytic lymphohistiocytosis; KD: Kawasaki disease; ADEM: Acute disseminated encephalomyelitis; ALERD: Acute leukoencephalitis with restricted diffusion; ANEC: Acute necrotizing encephalopathy of childhood; GBS: Guillain Barre syndrome; MG: Myasthenia gravis; AIHA: Autoimmune hemolytic anemia; MIS-C: Multisystem inflammatory syndrome in children.

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Citation: Varadarajan P, Subramani S, Jeyaram V, Velmurugan LS, Jayaseelan R, Venugopal GS. Study on intravenous immunoglobulin use in a pediatric intensive care unit of a tertiary care center. World J Clin Pediatr 2026; 15(2): 118421
URL: https://www.wjgnet.com/2219-2808/full/v15/i2/118421.htm
DOI: https://dx.doi.org/10.5409/wjcp.v15.i2.118421

Varadarajan P, Subramani S, Jeyaram V, Velmurugan LS, Jayaseelan R, Venugopal GS. Study on intravenous immunoglobulin use in a pediatric intensive care unit of a tertiary care center. World J Clin Pediatr 2026; 15(2): 118421 [PMID: 42220964 DOI: 10.5409/wjcp.v15.i2.118421]

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