Study on intravenous immunoglobulin use in a pediatric intensive care unit of a tertiary care center

doi:10.5409/wjcp.v15.i2.118421

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Jun 9, 2026; 15(2): 118421
Published online Jun 9, 2026. doi: 10.5409/wjcp.v15.i2.118421

Table 2 Hematological, cardiac and immunological indications, outcomes, and evidence for intravenous immunoglobulin use, n (%)

Condition (% of total)	Received IVIG	Survived	Recommendation	Evidence	Strength
Hematological (9.2)	42	25 (59.5)
AIHA	3	3 (100)	No	II	B
Secondary HLH	39	22 (56.4)	No	III	C
Cardiac (1.5)	7	6 (85.7)
Myocarditis	7	6 (85.7)	No	III	C
Immunological (42.4)	193	154 (79.8)
PID	11	5 (45.5)	Yes	Ia	A
Kawasaki disease	10	7 (71)	Yes	Ia	A
MIS-C	172	142 (82.6)	No	Ib	B

IVIG: Intravenous immunoglobulin; AIHA: Autoimmune hemolytic anemia; HLH: Hemophagocytic lymphohistiocytosis; PID: Primary immunodeficiency; MIS-C: Multisystem inflammatory syndrome in children.

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Citation: Varadarajan P, Subramani S, Jeyaram V, Velmurugan LS, Jayaseelan R, Venugopal GS. Study on intravenous immunoglobulin use in a pediatric intensive care unit of a tertiary care center. World J Clin Pediatr 2026; 15(2): 118421
URL: https://www.wjgnet.com/2219-2808/full/v15/i2/118421.htm
DOI: https://dx.doi.org/10.5409/wjcp.v15.i2.118421

Varadarajan P, Subramani S, Jeyaram V, Velmurugan LS, Jayaseelan R, Venugopal GS. Study on intravenous immunoglobulin use in a pediatric intensive care unit of a tertiary care center. World J Clin Pediatr 2026; 15(2): 118421 [PMID: 42220964 DOI: 10.5409/wjcp.v15.i2.118421]

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