Circulating levels of growth differentiation factor-15 and its genetic variants -3148C>G (rs4808793) in pediatric cardiac patients

Table 5 Genotypes and allele frequencies of growth differentiation factor-15 (rs4808793) single-nucleotide polymorphism among patients with and without heart failure

Study groups	Variables
	GDF-15 rs4808793 (-3148C>G) genotypes														GDF-15 rs4808793 (-3148C>G) alleles
	CC		CG		GG		CC+CG		GG		CC		CG+GG		C		G
	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%
Pediatric cardiac patients with heart failure (n = 50)	16	32	27	54	7	14	43	86	7	14	16	32	34	68	59	59	41	41
Pediatric cardiac patients without heart failure (n = 50)	20	40	26	52	4	8	46	92	4	8	20	40	30	60	66	66	34	34
P value (χ2)	0.527 (1.281)						0.338 (0.919)				0.405 (0.694)				0.307 (1.045)
OR (95%CI)							0.534 (0.146-1.954)				0.706 (0.311-1.603)				0.741 (0.417-1.317)

GDF-15: Growth differentiation factor-15; OR: Odds ratio; CI: Confidence interval.