Circulating levels of growth differentiation factor-15 and its genetic variants -3148C>G (rs4808793) in pediatric cardiac patients

Table 3 Genotypes and allele frequencies of growth differentiation factor-15 rs4808793 (-3148C>G) single-nucleotide polymorphism among the study groups

Study groups	Variables
	GDF-15 rs4808793 (-3148C>G) genotypes														GDF-15 rs4808793 (-3148C>G) alleles
	CC		CG		GG		CC + CG		GG		CC		CG + GG		C		G
	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%
Cases (n = 100)	36	36	53	53	11	11	89	89	11	11	36	36	64	64	125	62.5	75	37.5
Controls (n = 50)	5	10	34	68	11	22	39	78	11	22	5	10	45	90	44	44	56	56
P value (χ2)	0.002 (12.287)						0.073 (3.223)				< 0.001 (11.345)				0.002 (9.275)
OR (95%CI)	-						2.282 (0.913-5.707)				5.063 (1.844-13.902)				2.121 (1.302-3.455)

GDF-15: Growth differentiation factor-15; OR: Odds ratio; CI: Confidence interval.