Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study

doi:10.5409/wjcp.v15.i2.116098

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World Journal of Clinical Pediatrics

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2219-2808

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Jun 9, 2026; 15(2): 116098
Published online Jun 9, 2026. doi: 10.5409/wjcp.v15.i2.116098

Table 6 Correlation between serum ferritin, hemoglobin level, and heart rate variability parameters in β-thalassemia patients

Variable	HRV parameter	Spearman’s ρ	P value
Hemoglobin	LF power	0.230	0.154
	HF power	-0.188	0.244
	SDANN	-0.162	0.317
	RMSSD	-0.070	0.666
Serum ferritin	LF power	-0.096	0.557
	HF power	-0.012	0.943
	SDANN	0.194	0.230
	RMSSD	-0.130	0.425

Correlation between heart rate variability indices and laboratory parameters assessed using Spearman’s test. None of the correlations were statistically significant (P > 0.05). LF: Low frequency; HF: High frequency; SDANN: Standard deviation of the 5-minute mean normal-to-normal intervals; RMSSD: Root mean square of successive differences; HRV: Heart rate variability.

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Citation: Sorour EA, Elaskary EM, Elnemr SB, Hagag AA, Kassab NA, Al-Beltagi M. Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study. World J Clin Pediatr 2026; 15(2): 116098
URL: https://www.wjgnet.com/2219-2808/full/v15/i2/116098.htm
DOI: https://dx.doi.org/10.5409/wjcp.v15.i2.116098

Sorour EA, Elaskary EM, Elnemr SB, Hagag AA, Kassab NA, Al-Beltagi M. Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study. World J Clin Pediatr 2026; 15(2): 116098 [PMID: 42220932 DOI: 10.5409/wjcp.v15.i2.116098]

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