Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study

doi:10.5409/wjcp.v15.i2.116098

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Jun 9, 2026; 15(2): 116098
Published online Jun 9, 2026. doi: 10.5409/wjcp.v15.i2.116098

Table 5 Comparison between the two studied groups regarding different waves and intervals, median (25^th-75^th percentiles)/n (%)

		Patient group (n = 40)	Control group (n = 40)	P value
P wave	Amplitude (mm)	3 (2-3)	2 (2–3)	0.385
	Duration (second)	0.08 (0.08-0.08)	0.08 (0.08-0.09)	0.597
	Dispersion (second)	0.04 (0.04-0.04)	0.035 (0.02-0.04)	< 0.001
QRS complex	R wave amplitude in channel 1 (mm)	25 (23-26)	24 (23-24)	0.004
	R wave amplitude in in channel 2 (mm)	12 (8-15)	7 (4-10)	< 0.001
	S wave amplitude in in channel 1 (mm)	4 (2-7)	5 (3-7)	0.438
	S wave amplitude in channel 2 (mm)	7 (6-9)	7 (5-8)	0.081
	Duration (second)	0.12 (0.11-0.12)	0.08 (0.08-0.08)	< 0.001
PR interval	Constant	40 (100.0)	40 (100.0)
	1:1 AV conduction	40 (100.0)	40 (100.0)
	Duration (second)	0.16 (0.12-0.16)	0.12 (0.12-0.12)	< 0.001
ST segment	Normal	36 (90.0)	40 (100.0)	0.116
	Elevation	0 (0.0)	0 (0.0)
	Depression	4(10)	0 (0.0)	0.116
T wave abnormalities	Normal	39 (97.5)	40 (100.0)	1.000
T wave abnormalities	Inversion	1 (2.5)	0 (0.0)	1.000
QT corrected (msec)		464.5 (443-481)	405 (380-430)	< 0.001

AV: Atrioventricular.

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Citation: Sorour EA, Elaskary EM, Elnemr SB, Hagag AA, Kassab NA, Al-Beltagi M. Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study. World J Clin Pediatr 2026; 15(2): 116098
URL: https://www.wjgnet.com/2219-2808/full/v15/i2/116098.htm
DOI: https://dx.doi.org/10.5409/wjcp.v15.i2.116098

Sorour EA, Elaskary EM, Elnemr SB, Hagag AA, Kassab NA, Al-Beltagi M. Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study. World J Clin Pediatr 2026; 15(2): 116098 [PMID: 42220932 DOI: 10.5409/wjcp.v15.i2.116098]

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